Impact of Washing On Performance and Characteristics of Clay-Based Geopolymer Adsorbent See

The steep rise in human population and their exploitation of precious natural resources such as water have degraded the quality of ground and surface water over the years, and this is a matter of great concern. Dye pollution is a critical problem affecting water quality and aquatic ecosystems worldwide. Water treatment methods, such as clay-based adsorbents, have garnered significant attention due to their abundance, ready availability, simple synthesis processes, and potential for largescale...

Simulation and Hardware Realization of Open-loop SPS Controlled SiC-based DAB Converter for Battery Charging See

The use of SiC MOSFETs enables faster switching, reduced conduction losses and higher breakdown voltage, making them ideal for high-frequency isolated power conversion. This paper presents the design and simulation of a silicon carbide (SiC) based dual active bridge (DAB) converter for electric vehicle (EV) battery charging applications. The converter operates at a switching frequency of 50 kHz, interfacing a 400 V DC source with a 60 V battery load. The power transfer is obtained by using si...

Performance Analysis of a Direct Power Controlled VSC for PMSG based Wind Energy Conversion System See

Small-scale Permanent Magnet Synchronous Generator (PMSG) based Wind Energy Conversion System (WECS) widely uses diode rectifier for conversion from AC to DC due to their affordability and ease of use. But, this structure results in high current harmonics and poor power factor on the source side. Direct Power Control (DPC) is a well-established control approach for pulse width modulation (PWM) converter to obtain sinusoidal current waveform and unity power factor (UPF) at the source side. DPC...

Performance of Indian Ocean Land Atmosphere (IOLA) Model in Simulating Monsoon Depression See

Monsoon depressions (MD) are among the most important synoptic-scale systems of the Indian Summer Monsoon. As these systems contribute nearly half of the monsoon-season heavy rainfall, their accurate prediction is critical for agriculture, disaster management, and early warning systems. The Indian Ocean–Land–Atmosphere (IOLA) coupled mesoscale model is a high-resolution prediction framework designed to simulate a wide range of severe weather events over the Indian region. Built on the NMM dyn...

Intersecting Determinant of Child Mortality: The Role of Health Financing and Government Effectiveness in Developing Countries See

Ensuring sustainable development in health indicators remains a persistent challenge for developing countries, this is mostly because they don’t have enough resources and insufficient health infrastructure. Several countries have depended on foreign financing to tackle their health issues. In this context, health aid serves as a significant tool in helping developing nations to reduce health issues and improve child survival rates. This study examines the effect of health aid and Domestic Gov...

Impact of ENSO and IOD Events On Upper Ocean Heat and Salt Transport in Coupled Models over the Tropical Indian Ocean See

The present study investigates the performance of the 6th phase of coupled models in representing upper ocean heat and salt transport at different straits of the Tropical Indian Ocean (TIO) during El Niño-Southern Oscillation (ENSO) (El Niño and La Niña) and Indian Ocean Dipole (IOD) phases (positive and negative). To explore the mean features of the transport, the present study utilises CMIP6 models and Ocean Reanalysis System 5 (ORAS5) observations for the period from 1965 to 2014. The heat...

Red Weaver Ants (Oecophylla smaragdina) a Bounty Source of Therapeutic and Functional Ingredients: A Clean Label Technological Intervention for Their Extraction See

The increasing global population and demand for sustainable food systems have sparked interest in utilizing insects as alternative sustainable sources of high-quality lipids and proteins. Red weaver ants (Oecophylla smaragdina), offer a promising solution due to their nutrient-rich composition, medicinal history, and environmental resilience. In this integrated study, both lipid and protein components of red weaver ants and their eggs were valorized through green and innovative bioprocessing ...

Non-oxido and Dinuclear Oxido VIV-based Metallodrugs: Solution Study, Cytotoxicity, and Cellular Internalization See

In recent years, vanadium compounds have been extensively studied for their biological, medicinal, and other therapeutic applications.1,2 To date, only a limited number of non-oxido and dinuclear oxido VIV complexes have been studied, mainly for their potential use in anticancer studies. So, exploring the toxicity potential of non-oxido compared to dinuclear oxido VIV complexes could provide valuable insights into their solution-phase stability and biological effects. In this presentation, th...

Mitoxantrone Elicits the Crosstalk Between ROS-Dependent Elimination of Dysfunctional Mitochondria and Xenophagy Responses to Eliminate Intracellular Mycobacteria in Human Macrophages See

The rise of drug-resistant Mycobacterium tuberculosis has emerged as a global health emergency. Host-directed therapies that elevates innate immune responses offer a viable alternative. In this study, we investigated the potential of Mitoxantrone (MTX) as a host modulating agent with anti-mycobacterial activity. The cell viability assay confirmed that 1 µM MTX is non-toxic to dTHP-1 cells. Time kinetics experiments identified 12hrs treatment period as optimal for eliciting autophagic response...

Furamidine-Triggered Autophagy Mediates Anti-Mycobacterial Activity through Ca²⁺-Dependent SIRT1–AMPK–FOXO3a Signaling See

Mycobacterium tuberculosis (M. tb), the causative agent of human tuberculosis (TB), continues to be a significant cause of mortality worldwide. The latest findings have highlighted autophagy as a host-defence mechanism that eradicates many invading bacteria, including M. tb. Thus, novel approaches like the stimulation of autophagy using various pharmaceutical drugs can be undertaken to deal with this noxious pathogen. The present study has been formulated to evaluate the anti-mycobacterial po...

Mitoxantrone Activates IL-8 Dependent NF-κB Signalling Cascade to Elevate Mitochondrial Calcium and ROS, Triggering Mitophagy and Promoting Mycobacterial Clearance in dTHP-1 Cells See

Mitoxantrone, a topoisomerase II inhibitor with known immunomodulatory properties, has emerged as a potential regulator of mitochondrial quality control in macrophages In this study, we explored the role of NF κB IL 8 signalling in mitoxantrone mediated mitochondrial responses and its impact on mycobacterial clearance in differentiated THP 1 cells Our findings suggest that mitoxantrone triggers IL 8 activation, leading to upregulation of NF κB expression The autocrine IL 8 signalling promotes...

Dynamic Analysis of Multi-Bolted FRP Composite Joints Using a Virtual Material Interface and Viscoelastic Behaviour See

The uses of Fiber Reinforced Plastic (FRP) composite materials have grown vastly in modern day engineering because they exhibit a greater strength-to-weight ratio, resistance to corrosion, and tailored mechanical properties. Bolted joints are commonly employed in FRP structures due to their ease of assembly and disassembly. However, their structural integrity and vibration performance directly affect the serviceability and safety of these structures. In this study, a three-dimensional (3D) nu...

Epigenetics of Neuronal Differentiation: KIF5A Mediated Transport and Dynamics of Mitochondria During Neuron Development Is Facilitated by FAK Mediated Down Regulation of Chromatin Modifiers See

Well controlled development of mammals, including humans is the pre-requisite of fruitful reproduction. Nervous system plays distinct roles in reproduction. Aberrant gene expression and uncontrolled neuronal differentiation leads to neuroblastoma. Chromatin modifications, including DNA methylation and various types of chemical modifications of histone regulates gene expression. Neuronal stem cells differentiate into mature neurons essential for brain activities like memory, learning and cogni...

Edge-Driven Key Generation for Lightweight Image Encryption Using Hardware-Accelerated Sobel Filtering on PYNQ-Z2 See

The execution of image processing tasks on edge and IoT devices is always coupled with the need to develop encryption algorithms with a guarantee of security and low computation complexity. Most classical encryption algorithms employ a constant secret key and software-based implementation, making them unsuitable for resource-constrained devices and platforms. The study proposes the idea of implementing edgedriven key generation for hardware-assisted lightweight image encryption with Sobel edg...

UVIT-Selected Lyman Break Galaxies at z ~ 1 in GOODS-North See

We present here findings from a search for 22 Lyman Break Galaxies (LBGs) at a range of 0.7 ≤ z ≤ 1.2 in the Great Observatories Origins Deep Survey North (GOODS-N) field by UltraViolet Imaging Telescope (UVIT) on board ASTROSAT, employing the dropout technique. We present an estimation of the physical properties, including age, mass, and star formation rates (SFRs), of the LBG candidates using the spectral energy distribution (SED) fitting method, and their morphology.

Benchmarking the Indian Pharmaceutical Industry: A DEA-Tobit Analysis of Performance and Policy Implications See

India has emerged as a leading global centre for pharmaceutical production, playing a vital role in the global supply of cost-effective, high-quality generic medicines. Recognised as a key contributor to global healthcare security, the sector continues to expand in both scale and strategic importance. The present study evaluates the performance of major Indian pharmaceutical firms by examining their technical efficiency and the organisational attributes that shape it. A balanced panel dataset...

Understanding Undernourishment in South Asia: The Role of Political Stability See

Attaining the United Nations' Sustainable Development Goals (SDGs) 2.1, which focuses on nutritious and safe food for all, remains a major challenge due to the slow pace of reduction in undernourishment across South Asia countries. Home to a significant share of the world’s population, South Asia continues to face considerable challenges in ensuring its citizens have adequate access to nutritious food. Many countries in the region face persistent socioeconomic and political challenges that hi...

Development of Smart Socks for Real-Time Assessment of Knee Ankle Associated Functional Mobility in Patients During and Post-Rehabilitation See

A compact hardware module, approximately the size of a coin and weighing ~6 g, has been developed and integrated within Smart Socks for ambulatory assessment of lower-limb mobility in elderly individuals over extended durations ranging from 6 hours to 30 days. The system features onboard data logging of foot-mounted inertial sensor outputs, enabling continuous monitoring without dependency on external devices. A dedicated software interface, paired with the Smart Socks, processes and compares...

Integrative Multivariate Analysis and YOLOv5-Based Deep Learning for Quality Evaluation of Underutilized Hyacinth Bean (Lablab purpureus) Landraces See

The present study investigates the comprehensive quality and compositional profiling of twelve underutilized Hyacinth bean (Lablab purpureus) landrace accessions through a multidisciplinary approach integrating traditional analytical techniques with modern deep learning tools. Initially, we conducted an extensive evaluation of engineering properties, proximate composition, antinutritional factors, and mineral content (including essential minerals and heavy metals) for each accession. To extra...