In addition to the traditional library information retrieval (IR) practices, the modern library has implemented federated search, web discovery, next-generation cataloguing, and other new tools for effective organization and discovery. Facet navigation (facet search, facet navigation, or guided navigation) is applied to many e-commerce sites and dominates the interface paradigm features. The faceted approach to knowledge organization in search and navigation functions of online catalogues hel...

Wound healing is a naturally occurring process in our body and comprises various phases like hemostasis, inflammation, proliferation and remodeling. Bromelain, a natural cysteine protease, is a multifunctional molecule with analgesic and anti-inflammatory effects that aid in the treatment of wounds. This study focuses on developing chitosan/alginate bilayer film by incorporating bromelain (0,0.5,1,1.5 and 2% w/v) in the alginate layer via layer-by-layer assembly. Bilayer films were prepared b...

An exact forecast of the friction factor coefficient is crucial in hydraulic engineering, because it has a direct impact on the design of hydraulic structures, the computation of velocity distribution, and the precise estimation of energy losses. Friction factor of a channel is a kind of frictional force that prevents the river from moving forward as it flows downhill, and basically it depends on the smoothness or roughness of the channel. This study is an attempt to rank the input parameters...

Osman Sagar was created by damming the Musi River in 1920, to provide an additional source of drinking water for Hyderabad and to protect the city after the great Musi River flood of 1908.The flood problem and the shortage of drinking water problem have been solved after the Nizam consulted Sri Sir M. Visvesvaraya. The Osman Sagar and Himayat Sagar lakes are home for large number of native plant and animal species, therefore water quality and health of the lake are vital for conservation of t...

Oral Squamous cell carcinoma is one of predominant cancer in India. Mitophagy, the selective elimination of damaged mitochondria, strongly impacts the progression of diverse cancer types, including oral cancer, by favoring cell survival within the tumor microenvironment. The mitochondrial pyrophosphatase or inorganic pyrophosphatase 2 (PPA2) is a mitochondrial matrix localized protein known for maintaining mitochondrial membrane potential. We have investigated the expression of PPA2 in differ...

Various flow characteristics such as velocity distributions, turbulence characteristics, mass and momentum exchange between the vegetated and non-vegetated regions. Aquatic plants are responsible for reducing sediment transport, erosion control and turbidity, water quality, nutrient and particulate removal significantly. The studying and understanding of the vegetation effect on the natural flow is an important objective in modern scientific research about flow structure, flood control, river...

Generally, the flow in natural rivers is unsteady. Accurate assessment of various flow properties like friction velocity and bed shear stress in an open channel flow under unsteady condition is of crucial importance to hydraulic engineers since it helps in estimation of erosion, sediment transport etc. Bed shear stress can be properly predicted by accurate calculation of the friction velocity which is generally influenced by the geometry, roughness, and hydraulic parameters of the channel. In...

SIRT1 (NAD-dependent protein deacetylase sirtuin-1), a class III HDAC acting as a tumor suppressor gene, is downregulated in oral cancer cells. Optimal doses of cisplatin (CDDP) are found to downregulate SIRT1 expression advocating the mechanism of drug resistance. SIRT1 downregulation orchestrates inhibition of DNM1L-mediated mitochondrial fission, subsequently leading to the formation of hyperfused mitochondrial networks. The hyperfused mitochondrial networks preserve the release of cytochr...

Electrochemical techniques are widely used for biosensing applications. Previous work has focused on the development of sensor readout circuits for any one of the electrochemical techniques. However, many sensors face the problem of sensor degradation, which can be estimated using sensor impedance. Amperometry for biosensing applications and impedance spectroscopy for study of sensor impedance can be utilized to study the impact of biofouling on sensor layers. In this paper, we have attempted...

Physical inactivity has a substantial negative influence on one’s health, lowers quality of life, and frequently causes cardiovascular disease, diabetes, and mobility problems. Both diabetes and the patient’s lifestyle have a significant impact on each other. Although we shouldn’t overburden most diabetes patients with technology since they can manage their condition without it, lifestyle-monitoring technology can nevertheless be helpful for both patients and their doctors. As a result, we cr...

Understanding the mass balance between the ocean and the land requires estimating sediment yield. Direct measurement of suspended sediment is challenging considering the time and money required. The suspended sediment yield is influenced by several variables, all of which have non-linear and complex interrelationships. This study proposed artificial intelligence algorithms such as Artificial Neural Networks (ANN) to estimate the suspended sediment yield in Mahanadi River Basin. The hydro-clim...

A cost-efficient healthcare system is a prerequisite for the sustainable economic development of a country and an inevitable booster factor for overall macroeconomic performances, including institutional arrangements and incentive sentiments of foreign investors. Therefore, this study empirically investigates the three-way nexus between bilateral FDI, institutional quality, and health expenditure in 19 selected G20 economies from 2009 to 2017. Our analysis employs three sets of equations to a...

Wound healing is a dynamic and intricate process that aims to return damaged tissue's cellular composi tion and layers as closely as possible to their pre-damaged state. Catharanthus roseus is a medicinal plant with excellent anti-cancer, anti-microbial, and anti-fungal properties. In this study, ethanol extract of C. roseus leaf and flower was extracted and were analyzed qualitatively and quantitatively. The results show that the total flavonoid and phenol content was much higher in the leaf...

In this study, we examine how debt financing in general and bank borrowings in particular affect the earnings quality in Indian firms. We conduct an empirical analysis taking a sample of 626 Indian non-financial firms from 2003 to 2021. Our sample comes from the Food and Agro-based industry, which is divided into four relatively homogenous groups. On each of the groups, we apply an industry-wise cross-sectional version of modified Jones model (Dechow et al. 1995) for estimating the discretion...

Background: In occupational health psychology, burnout is a frequently investigated issue. Burnout is one of the global workplace health issues concerning human health and quality living life. The workers in the mining industry are susceptible to burnout issues, but minimal qualitative research has examined the factors contributing to burnout. This understanding could enable the development of future burnout prevention measures and policies. Objective: The study explored the essential fa...

Flood risks are among the many water-related concerns that have the potential to cause the most damage. Urban flooding and the risk it poses are growing issues with global significance, but they are especially serious in developing nations like India, where the risk is typically understudied and little understood. Consequently, it is crucial to develop a stage-discharge model that would aid in flood prediction. In comparison to the past, floods in mountainous areas are increasingly more frequ...

Mitophagy involves the selective elimination of defective mitochondria during chemotherapeutic stress to maintain mitochondrial homeostasis and sustain cancer growth. Here, we showed that CLU (clusterin) is localized to mitochondria to induce mitophagy controlling mitochondrial damage in oral cancer cells. Moreover, overexpression and knockdown of CLU establish its mitophagy-specific role, where CLU coordinately interacts with BAX and LC3 forming a tri-complex to clear damaged mitochondria in...

The study and estimation of river bed load transport fluctuation is very complex for supplementing existing sediment transport theory. Fluctuation of bed load depends on several scales, including individual particle motion, the development of bed forms, the presence of bed load sheets, and waves of stored sediment. The essential characteristic of a river channel is to percolate the water in terms of downward seepage because of the permeability of sandy materials. Further, the problem of seepa...

Utilization of spatial multiplexing and diversity gain in massive multiple-input multiple-output (MIMO), requires availability of the downlink channel state information (CSI) at the base station. Frequency division duplex (FDD) systems use different uplink and downlink channels and it limits the use of reciprocity. Downlink precoding computations requires channel responses of the downlink to be estimated and the base station (BS) is fed back with those estimated channel responses. The matrix ...