DSpace@nitr >
National Institue of Technology- Rourkela >
Conference Papers >

Please use this identifier to cite or link to this item: http://hdl.handle.net/2080/1632

Full metadata record

DC FieldValueLanguage
contributor.authorParida, P-
contributor.authorBehera, Ajit-
contributor.authorSwain, S K-
contributor.authorMishra, S C-
date.accessioned2012-02-27T09:54:37Z-
date.available2012-02-27T09:54:37Z-
date.issued2011-12-
identifier.citationNational Conference on Processing and Characterization of Materials (NCPCM-2011), Department of Metallurgical & Materials Engineering, 2-3 December 2011, National Institute of Technology, Rourkelaen
identifier.urihttp://hdl.handle.net/2080/1632-
descriptionCopyright belongs to proceeding publisheren
description.abstractNanoparticles are widely due as sustained drug delivery system. Due to their smaller size of controlled drug release potential, targeting ability, enhancement of therapeutic efficacy and reduction of toxicity. Nifedipine one of the calcium channel blocker use for the management of hypertension. Spray drier technique develops Nifedipine loaded nanoparticle. Primary superimulsion phase contains Drug (Nifedipine), Polymer (Ethylcellulose) & suitable non-aqueous Solvent (Dichloromethane) which are sprayed over secondary phase containing aqueous solvent with dispersing polymers (PVA). Formation of films on the surface of secondary phase dried, sieved & forward to spectroscopic analysis. FTIR spectrometer as an analytical tool shows the final formulation retains its chemical groups with nucleus (dihydropyridine) indicates no fluctuation at drug stability. DSC study shows the glass transition remains likely constanten
format.extent245364 bytes-
format.mimetypeapplication/pdf-
language.isoen-
subjectNanoparticlesen
subjectDrug Deliveryen
subjectNifedipineen
subjectSpray drier techniqueen
titleCharacterisation of Nanoparticle through SEM, FTIR & DSCen
typeArticleen
Appears in Collections:Conference Papers

Files in This Item:

File Description SizeFormat
Characterisation.pdf239KbAdobe PDFView/Open

Show simple item record

All items in DSpace are protected by copyright, with all rights reserved.

 

Powered by DSpace Feedback