|
DSpace@nitr >
National Institue of Technology- Rourkela >
Journal Articles >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/2080/1593
|
| Title: | Determination of Physical Characteristics of Nifedipine Microsphere |
| Authors: | Parida, P
Mishra, S C |
| Keywords: | Nifedipine
Microsphere
Polymer
SEM
DSC |
| Issue Date: | Aug-2011 |
| Publisher: | Orissa Physical Society |
| Citation: | Orissa Journal of Physics, Vol. 18, No.2, August 2011, pp. 221-225 |
| Abstract: | We performed the quantitative physical identification of Nifedipine
microsphere which shows sustained release action for the Hypertensive patients. The drug
used as calcium channel blocker. Here the process of Analytical developmental study
helps quantify the content in raw materials and in formulation of test samples. Nifedipine
microsphere was prepared by solvent evaporation technique. Spherical microspheres
having good entrapment efficiency surface characteristics. From SEM study it was found
the image of the formulation. The properties of microspheres were found to be changed
by various processing parameters to give microspheres of better flow property. The goal
of this work was to investigate the influence of some process parameters on physical
characteristic of microsphere. From the DSC analysis it was found that the transition
temperature of Nifedipine microsphere remains nearly to Nifedipine pure drug which
determine the significant parameter and efficient in swellin... |
| Description: | Copyright belongs to Orissa Physical Society |
| URI: | http://hdl.handle.net/2080/1593 |
| ISSN: | 0974-8202 |
| Appears in Collections: | Journal Articles
|
Files in This Item:
| File |
Description |
Size | Format |
|---|
| OJP_18_2_0511_59.pdf | | 1532Kb | Adobe PDF | View/Open |
|
Show full item record
All items in DSpace are protected by copyright, with all rights reserved.
|
