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Please use this identifier to cite or link to this item: http://hdl.handle.net/2080/1552

Title: Analytical Characterization of a Gelling Biodegradable Polymer
Authors: Sahoo, S
Chakraborti, C K
Mishra, S C
Naik, S
Keywords: HPMC
FTIR
Raman spectroscopic analysis
XRD study
Issue Date: Jun-2011
Publisher: Drug Invention Today (DIT)
Citation: Drug Invention Today, 2011, 3(6)
Abstract: The present study was undertaken for the analytical characterization of a hydrophilic biodegradable polymer, Hydroxypropyl methylcellulose (HPMC). Purity and the crystalline nature of the polymer were evaluated. Fourier Transform Infrared (FTIR) analysis was performed by FTIR Spectrophotometer interfaced with infrared (IR) microscope operated in reflectance mode. The spectra were collected over the wave number from 400 to 4000 cm-1 at room temperature. Raman spectroscopic analysis for the polymer was performed by a low resolution portable Raman Spectrometer (Raman system R-3000), using 785 nm solid state diode laser, with fiber optic sampling probe. The Raman spectra were collected over the wave number from 140 to 2500 cm-1 at room temperature. X-ray powder diffraction (XRD) data for HPMC polymer were obtained using a powder diffractometer. The polymer was scanned from a Bragg angle (2è) between 100 and 700. The obtained data were tabulated in terms of the lattice spacing (Å) and r...
Description: Copyright belongs to Drug Invention Today (DIT)
URI: http://hdl.handle.net/2080/1552
ISSN: 0975-7619
Appears in Collections:Journal Articles

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