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Emerging evidences highlight a significant association of aberrant mitochondrial function with drug resistance and increased proliferation in cancer. Cancer cells modulate mitochondrial dynamics to counteract chemotherapy stress. Excessive stress causes mtDNA to leak out and drive an inflammatory response. The inner mitochondrial protein MTP18 executes mitochondrial fission and has an LIR motif that interacts with LC3 and promotes mitophagy. This study explores the role of an inner mitochondr...
Mitochondria are the key players in maintaining cellular health by critically regulating metabolic processes, stress adaptation through cellular survival, and redox balance. They govern these by a synchronized process of mitochondrial homeostasis through fission and fusion cycles, facilitating a segregation of dysfunctional mitochondria from a healthy population and enabling either their repair or destruction by targeting them through the mitophagy pathway. However, excessive stress also lead...
The seasonal summer monsoon rainfall over India has substantially depended on the synopticscale systems such as monsoon lows and depressions. India has received above-average rainfall during the 2020 summer monsoon season. Total 12 Low Pressure Areas (LPAs) formed in the north Indian Ocean during summer 2020 (in JJAS season). The significance of this monsoon season is that August 2020 received the highest all-India rainfall in the past 44 years since 1976. This is accompanied by around 50% of...
The exodus of Kashmiri Pandits from the Valley during the 1990s led to the trauma of reestablishing their lives in an alien territory, which Rahul Pandita called ‘Shahar’ or city. Rahul Pandita, a prominent journalist and writer, works on exploring the undocumented narrative of the exodus and the trauma of being a refugee in one’s country, which is reflected in his memoir, Our Moon Has Blood Clots: A Memoir of a Lost Home in Kashmir (2013). The focus of this study is to analyse one of the key...
The effective utilization of waste materials plays a critical role in advancing sustainability efforts. Tire-derived aggregates (TDAs), offer a promising lightweight alternative for backfill behind retaining walls. This study investigates the potential of sand-TDA mixtures, prepared in varying proportions, to replace any synthetic light-weight materials as backfill. A numerical retaining wall model was developed using the RS2 finite element software to evaluate the performance of sand, TDAs, ...
Artificial intelligence and computer vision advancements have revolutionized computer-aided diagnosis (CAD) systems, enabling more accurate breast cancer (Br-Can) detection using histopathology images. This study proposes a classification framework that integrates Vision Transformers (ViT), Graph Attention Networks (GAT), and Calibrated Random Forest (CRF) to enhance diagnostic accuracy. ViT effectively captures rich visual representations and helps to form a graph-like structure, while GAT m...
Development of polymer-based scaffolds incorporating phytomolecules is crucial for enhancing the osteogenic properties of polymeric bone substitutes. In this study, novel 3D printed scaffolds composed of sodium alginate (SA) and chitosan (CH), loaded with Cissus quadrangularis (CQ) seed extract, were successfully fabricated, and their morphology was characterized using scanning electron microscopy (SEM). Incorporation of CQ extract in SA/CH scaffold improved the hydrophilicity and biodegradat...
This study presents an unravelling intricate magnetic behaviour involving spin reorientation (SR) and exchange bias (EB) along with dielectric relaxation behaviour in polycrystalline Y1-xSmxCrO3 (0 ≤ x ≤ 0.3) compounds. The X-ray diffraction spectra reveal the phase purity of compounds, which are crystallized through distorted orthorhombic structures (Pnma space group). Surface morphology confirms that Sm doping decreases average grain size from 0.43 to 0.35 µm. The temperature-dependent magn...
Two-dimensional (2D) materials have attracted vast research interest since the breakthrough discovery of graphene. One major benefit of such systems is the ability to tune the Fermi level through the charge neutrality point between electron and hole doping. In this presentation, we show that single layer graphene coupled to the low-density superconductor indium oxide (InO) exhibits two charge neutrality points, each of them representing electronic regions in which the carrier density can be t...
The conception of objects as enclosed, discrete, and immanent material has been historically challenged by the theoretical frameworks of Post-Humanist thinkers and Material Cultural theorists, who have foregrounded the historical, affective, socio-political, and cultural embeddedness of objects. The material turn in Memory Studies, examining evocative objects or material possessions, is essentially limited to studies on Partition, indentured labour, refugee narratives, and culinary identities...
The characterization of atrial repolarization (Ta wave) remains largely elusive due to its inherently low amplitude and concealment beneath the dominant QRS complex. Hence, this study aims to witness Ta wave within QRS complex using spline interpolation framework. 10-second ECGs of 50 Sinus Tachycardia (SiT) and 20 Atrial Tachycardia (AT) were recorded using standard 12-lead. Lead-II signals were pre-processed for noise removal and fiducial points detection. Later, three spline models were us...
Rechargeable Li-ion batteries are essential for modern society by enabling portable electronics, electric vehicles, and renewable energy storage. As a main component, electrolytes play a pivotal role in the operation and performance of Li-ion batteries by enabling the transport of Li-ions between the anode and cathode during charge and discharge cycles. An ideal electrolyte must exhibit high ionic conductivity, wide electrochemical stability, and compatibility with electrode materials. By com...
While history often relies on a pretence of objectivity, what is remembered as history is woven tightly with selected remembrance. In Anuradha Roy’s fiction, memory is more than remembering—it takes place as a memory-site, a site of women’s muted memories where repressed experiences have been recalled, resisted, and re-invented. This paper examines An Atlas of Impossible Longing (2008) and Sleeping on Jupiter (2015), positing that domestic and religious spaces function as archives worthy of b...
Lipid bilayers, the fundamental components of biological cell membranes, are known to be stabilized and functionally preserved in the presence of certain small saccharides-under various environmental stresses. In contrast, short-chain aliphatic alcohols are well-documented for their disruptive effects on membrane structure. Their interaction with lipid bilayers often leads to increased permeability, uncontrolled solute transport, and leakage of essential cofactors. While lipid-saccharide inte...
Internet of Things (IoT) and Blockchain integration are having a huge impact on the future of technological progress. IoT has progressed from an emerging notion to a widely used technology, shaping the future of digital connectivity. With billions of networked IoT devices generating large amounts of data, efficient data management becomes critical. Blockchain has been explored extensively to enhance security in IoT networks however, its scalability limitations become evident when handl...
In the current volatile, uncertain, complex, and ambiguous technological landscape, the manufacturing sector of emerging economies faces critical challenges such as employee disengagement, escalating stress levels, and high attrition rates. While artificial intelligence (AI) is increasingly integrated into workplace processes, limited research examines AI sensation, employee sustainability, and its impact on employees’ emotional response. Addressing this gap, the present examines the impact o...
Mining enclaves inhabited by Particularly Vulnerable Tribal Groups (PVTGs) in Odisha display the dynamic of exclusionary development that creates spaces of relentless accumulation alongside precarity. There is a need to make sense of the mineral-based development strategy, which is constituted by and constitutive of spatialisation of tribal precarity. It is also essential to examine how the mining-affected PVTGs exercise the agency to deal with precarity. Extant Indian literature does not spe...
Internet of Things (IoT) and Blockchain integration are having a huge impact on the future of technological progress. IoT has progressed from an emerging notion to a widely used technology, shaping the future of digital connectivity. With billions of networked IoT devices generating large amounts of data, efficient data management becomes critical. Blockchain has been explored extensively to enhance security in IoT networks however, its scalability limitations become evident when handling lar...
This work aims to provide a machine learning inspired design technique of fractal gasket antenna (FGA). Considering the diverse applications of fractal gasket antenna in providing high pattern diversity, low cross-polarization, etc., it has become a popular candidate in next generation planar pcb technology. The planar structure of the fractal gasket provides the benefit of easier integration with other circuit components. However, the design and analysis of FGA is dominantly done through ful...
The k-Generalized Fibonacci sequence is a generalization of the classic Fibonacci sequence with some fixed integer k ≥ 2. In this paper, we identify all k-Generalized Fibonacci numbers which can be represented as concatenation of three repdigits. This work builds upon and extends the previous research by Erduvan and Keskin, who identified all the Fibonacci numbers with this property. Using the former result we explore all the k−Generalized Fibonacci numbers, which can be expressed as the diff...
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