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Polyphenols are naturally occurring plant-derived secondary metabolites that influence postprandial glucose homeostasis by modulating enzymatic starch breakdown. Polyphenols, particularly flavonoids and phenolic acids, are reported to enhance insulin action and lower postprandial glucose levels by modulating oxidative stress, inflammation, and enzymatic pathways of starch hydrolysis. The present study investigates the inhibitory effect of selected dietary polyphenols on starch hydrolysis usin...
Slope stability assessment is essential for ensuring the safety and sustainability of civil engineering projects such as dams, highways, and excavations. The conventional analysis procedures, such as limit equilibrium and numerical simulation, are usually insufficient to handle the complex as well as the nonlinear characteristics of soil and rock masses under varying environmental circumstances. The paper will present a critical review of recent developments in the field of predicting slope s...
This numerical investigation examines the influence of fragmented channel placement and channel configuration in a circuitous minichannel cold plate incorporating flow fragmentation, aimed at enhancing heat transfer in an indirect liquid-cooled lithium-ion battery module. A dual-potential multi-scale, multi-domain (MSMD) modeling framework is employed to represent the battery behavior. The electrochemical processes within the battery are captured using the Newman–Tiedemann–Gu–Kim (NTGK) m...
Time series forecasting on graph-structured data is an important problem in various fields such as tracing diseases, teaching, and social networks. Graph Neural Network (GNN)-based models, presently used in most applications, often assume a unimodal distribution for future predictions, making it incapable of grappling with the uncertainty and multi-modal nature of real-life datasets. In this paper, we propose a novel residual learning-based hybrid technique that integrates the Semantic Graph...
The adoption of agricultural insurance remains constrained, primarily due to persistent challenges in accurately assessing risk. This study develops a climate-responsive insurance framework that integrates meteorological observations and remote sensing indicators into advanced statistical modeling to improve risk assessment. Historical yield observations and weather data are analyzed across three key crop life cycle stages: sowing, growing, and harvesting, to estimate the predictive yield den...
Proto-neutron stars (PNSs) are the hot, lepton-rich remnants of the core collapse supernovae, which go through a cooling phase and become cold, stable Neutron stars (NSs). Since PNSs are also superdense objects with strong gravitational fields, we can use them to probe general relativity (GR) in the high-curvature regime, similar to NSs. In this study, we analyze the macroscopic properties of PNSs using three different relativistic mean-field (RMF) equations of state (EOSs) with fixed entro...
Industrial wastewater treatment has been a serious global issue in recent decades, and waste management necessitates the invention of new, cost-effective, sustainable technologies. There is a massive demand for potential wastewater purification methods using eco-friendly, low-cost material. Adsorption is the most affordable, reliable, and operationally quick wastewater treatment method. In the 21st century, there is a rising demand for environmentally friendly porous geopolymer adsorbents th...
Concrete has an intricate internal structure exhibiting non-linear postpeak softening and quasibrittle fracture behavior. To accurately capture its mechanical and failure behavior, it is imperative to understand the interaction between major constituting phases of concrete. In this study, the effect of aggregate shape and volume fraction on mesoscale fracture of geometrically similar beams have been investigated. A two-dimensional mesoscale model consisting of mortar, aggregate and interfacia...
In this problem the existence of a normalized solution with prescribed mass a > 0 for a class of Sobolev critical free boundary problems will be proved. The concentration–compactness principle is utilized to overcome the lack of compactness induced by the critical nonlinearity. The argument is based on elliptic regularity and a mountain pass framework in a constrained variational setting.
In this study, we undertake a detailed classification of families of lines in the three-dimensional projective space PG(3, q2) that fulfill a prescribed set of incidence conditions. Our investigation reveals that such line families can be precisely characterized in two distinct ways. Specifically, we demonstrate that these families either correspond to the set of all lines intersecting a Hermitian variety of PG(3, q2) in exactly q + 1 points, or they form part of a certain conjectural or “hy...
Two-dimensional (2D) material-based Field-effect transistors (FETs) are the future for digital technologies due to their excellent scalability and superior material properties compared to conventional silicon material. However, accurately and efficiently modeling these devices remains challenging due to quantum mechanical effects, which complicate transport through 2D materials. In this work, a compact modeling framework for the n-type and p-type 2D material FETs is proposed and implemented...
High precision time series photometry from space telescopes together with high-resolution spectroscopy has opened up new prospects in the study of massive B-type stars. These observations have revealed significant and diverse variabilities in the class of B supergiants. The origin of these variabilities is not fully understood but some of them may be associated with stellar pulsation. HD37128 (Epsilon Orionis) is a highly luminous B-type supergiant located in the constellation of Orion. The v...
The Mitogen Activated Protein Kinase (MAPK) pathway, comprising KRAS, BRAF, MEK, and ERK, regulates cell proliferation, differentiation, and survival. Dysregulated MAPK signaling drives tumor growth in ovarian, colorectal, lung, and breast cancers, making it a critical target for therapy. Statins, widely prescribed HMG CoA reductase inhibitors, block the mevalonate pathway and prevent RAS prenylation, indirectly suppressing MAPK activation. This connection highlights statins as promising cand...
Glycosylation significantly influences the properties and functions of peptides by attaching carbohydrate groups to specific amino acids. This modification can enhance peptide stability, solubility, and resistance to enzymatic degradation, while also affecting folding and overall structure.1 There are some contradictory studies suggesting that glycation can enhance peptide–peptide association enthalpy, reduce conformational entropy, and promote β-sheet-rich aggregate formation.2 Driven by suc...
High-speed video acquisition over Ethernet on FPGA platforms presents significant challenges due to strict real-time bandwidth requirements and susceptibility to packet jitter and synchronization errors. Asynchronous FIFO buffers play a critical role in such systems by decoupling write and read clock domains, thereby ensuring continuous and reliable data flow. This paper presents a custom dual-clock FIFO architecture for real-time video acquisition in IoT-based FPGA systems. Ethernet payloads...
This study investigated the effect of curing on the moisture loss and volumetric properties of Cold Mix Asphalt (CMA) with different filler materials such as cement, fly ash, Ground Granulated Blast-furnace Slag (GGBS), and lime. The major research scope encompassed the preparation of three types of CMA, monitoring the moisture loss, estimating the void properties with progressive curing, and determining the impacts of filler on moisture loss. A total of 36 samples were prepared and subjected...
This study aimed to establish a correlation between the gradation characteristics and mix properties of Cold Mix Asphalt (CMA) by evaluating the gradation. The major scope of this study included the selection of aggregate gradation envelope, characterization using analytical methods, determination of mix design parameters of CMA, and establishing a correlation between aggregate gradation and mix design properties of CMA. Initially, three gradations with different Nominal Maximum Aggregate (NM...
Sodium-ion batteries (SIBs) are promising alternative to lithium-ion batteries due to sodium’s abundance, low cost, and favourable electrochemical properties. However, the use of liquid electrolytes poses challenges such as leakage, flammability, and low electrochemical stability. As a solution, the NASICON-type solid-state electrolyte, Na3Zr2Si2PO12 (NZSP), emerges as a potential candidate for all-solid-state Na batteries, aiming to replace traditional liquid electrolytes used in Na-ion batt...
Graph coloring is a well-known NP-complete problem with applications in scheduling, register allocation, frequency assignment, and network optimization. Quantum computing offers the potential for polynomial or even superpolynomial speedups in certain problem instances, yet practical quantum graph coloring methods must carefully balance qubit resources, circuit depth, and constraint enforcement. We proposed a solver agnostic quantum framework for Kcoloring. Along with a novel encoding and eff...
Friedreich’s ataxia (FRDA) is an autosomal recessive neurodegenerative disorder caused by a GAA trinucleotide repeat expansion in the frataxin (FXN) gene, leading to decreased frataxin expression. Frataxin is crucial for iron–sulfur cluster assembly and mitochondrial health. Its deficiency results in mitochondrial iron overload, impaired respiratory chain function, and increased production of reactive oxygen species (ROS), creating a cycle of oxidative stress and iron toxicity. This, in turn,...
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- 40 Pati, U C
- 40 Ray, P K
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