Please use this identifier to cite or link to this item:
http://hdl.handle.net/2080/4417
Title: | Vicinal-diols as Promoters in MBH Reaction: An Efficient Protocol for Scantly Reported Aliphatic Aldehydes |
Authors: | Mandal, Sukanya Panda, Jeetendra Sahoo, Gokarneswar |
Keywords: | Vicinal-diols MBH Reaction Aldehydes |
Issue Date: | Feb-2024 |
Citation: | 32nd CRSI National Symposium in Chemistry (CRSI-NSC-32) and CRSI-RSC Symposium, BITS Pilani, 1-4 February 2024 |
Abstract: | This work proposes an integrated strategy to mitigate the sluggishness of sp 2 -C electrophiles, particularly aliphatic aldehydes, in MBH reactions with various pro-nucleophiles. 1,2-diols have been found to activate MBH precursors, enabling a faster, more efficient approach with an array of substrate scope, particularly for rarely reported aliphatic aldehydes as electrophile. The in-situ transesterification of the MBH adduct with glycol provided direct access to bioactive natural compounds against Leishmania Proteases. |
Description: | Copyright belongs to proceeding publisher |
URI: | http://hdl.handle.net/2080/4417 |
Appears in Collections: | Conference Papers |
Files in This Item:
File | Description | Size | Format | |
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2024_CRSI_SMandal_Vicinal-diols.pdf | Poster | 1.07 MB | Adobe PDF | View/Open Request a copy |
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