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http://hdl.handle.net/2080/4131
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DC Field | Value | Language |
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dc.contributor.author | Roy, Samadrita | - |
dc.contributor.author | Verma, Devendra | - |
dc.date.accessioned | 2023-12-18T04:41:20Z | - |
dc.date.available | 2023-12-18T04:41:20Z | - |
dc.date.issued | 2023-12 | - |
dc.identifier.citation | International Conference on Biomedical Materials and Technology (BioTEx), IIT Delhi, India, 29th November 2023 to 1st December 2023 | en_US |
dc.identifier.uri | http://hdl.handle.net/2080/4131 | - |
dc.description | Copyright belongs to proceeding publisher | en_US |
dc.description.abstract | Non-compressible hemorrhage is responsible for a significant number of deaths in civilian settings occurring worldwide annually. Addressing this critical issue, there is an urgent need to develop hemostatic biomaterials for rapidly controlling hemorrhage. Therefore, this study focuses on developing disintegrating hemostatic biomaterials for noncompressible bleeding. The device is in the form of pellets, which disintegrate quickly upon contact with blood due to fast absorption of blood by the device. Maximization of the surface area of the device by disintegration leads to enhanced blood absorption, causing quick breakdown of the pellets, resulting in rapid blood clotting. The hemostatic device consists of nanofibrous polyelectrolyte complex composed of natural polymers, disintegrating agents, and nanoparticles. The least clotting time recorded was 72±2 seconds. The FESEM images have shown the nanofibrous morphology of the prepared device, which influences the rapid absorption of blood and, therefore, reduces clotting time. The device was determined to be hemocompatible, with hemolysis 70%, indicating high cytocompatibility of the fabricated device. It can be suggested that the device can potentially control noncompressible hemorrhage. | en_US |
dc.subject | Blood absorption | en_US |
dc.subject | Disintegration | en_US |
dc.subject | Hemostasis | en_US |
dc.subject | Hemostatic device | en_US |
dc.subject | NonCompressible Hemorrhage | en_US |
dc.subject | Polyelectrolyte Complex | en_US |
dc.title | Development of Hemostatic Device for Non-Compressible Hemorrhage | en_US |
dc.type | Presentation | en_US |
Appears in Collections: | Conference Papers |
Files in This Item:
File | Description | Size | Format | |
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2023_BioTEX_ SRoy_Development.pdf | Poster | 843.94 kB | Adobe PDF | View/Open Request a copy |
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