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http://hdl.handle.net/2080/3734
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DC Field | Value | Language |
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dc.contributor.author | Panda, Snigdharani | - |
dc.contributor.author | Pattnayak, Bibek Chaw | - |
dc.contributor.author | Dash, Priyanka | - |
dc.contributor.author | Nayak, Bismita | - |
dc.contributor.author | Mohapatra, Sasmita | - |
dc.date.accessioned | 2022-09-06T06:44:26Z | - |
dc.date.available | 2022-09-06T06:44:26Z | - |
dc.date.issued | 2022-08 | - |
dc.identifier.citation | 161st Birth Anniversary Acharya P. C. Ray & International Seminar on Recent Advances in Chemistry and Material Science (RACMS – 2022) | en_US |
dc.identifier.uri | http://hdl.handle.net/2080/3734 | - |
dc.description | Copyright belongs to proceeding publisher | en_US |
dc.description.abstract | The improper use of antibiotics results in the emergence of drugresistant microbes which is a serious concern to public health. Here, an NIRstimulated fluorescent antibacterial gel has been formulated by encapsulating papaya leaf-derived carbon dots (PCQDs) in a thermosensitive PVA-melamine hydrogel. This antibacterial gel can release anticancer drug 5-Fu in a spatiotemporal and dosage-controlled manner under the exposure of a 980 nm NIR laser. PCQDs can precisely generate the photothermal effect and reactive oxygen species (ROS) under NIR which induce a significant antibacterial activity in both Gram-positive and Gram-negative bacteria in a controlled manner. At the same time, a customized delivery of 5-Fu minimizes the side effect of the drug. Consequently, this innovatively designed fluorescent gel exhibited an antimicrobial effect and can act as a promising material for the NIR-responsive release of anticancer drug 5-Fu as demonstrated in B16F10 melanoma cells | en_US |
dc.subject | hydrogel | en_US |
dc.subject | photodynamic | en_US |
dc.subject | eactive oxygen species (ROS) | en_US |
dc.subject | nanodrug | en_US |
dc.title | Papaya-Derived Carbon-Dot-Loaded Fluorescent Hydrogel for NIR-Stimulated Photochemotherapy and Antibacterial Activity | en_US |
Appears in Collections: | Conference Papers |
Files in This Item:
File | Description | Size | Format | |
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pattanakiB_RACMS0222.pdf | 1.12 MB | Adobe PDF | View/Open |
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