Please use this identifier to cite or link to this item: http://hdl.handle.net/2080/2768
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dc.contributor.authorSarkar, Debayan-
dc.date.accessioned2017-10-10T05:09:30Z-
dc.date.available2017-10-10T05:09:30Z-
dc.date.issued2017-08-
dc.identifier.citationRSC Seminar, Kolkata, India, 18 August, 2017.en_US
dc.identifier.urihttp://hdl.handle.net/2080/2768-
dc.descriptionCopyright of this document is with proceedings publisher.en_US
dc.description.abstractAt the heart of any chemical synthesis of a natural product or designed small molecule is the need to orchestrate a series of chemical reactions to prepare and functionalize a carbon framework. The advent of transition-metal catalysis has provided chemists with a broad range of new tools to forge C−C and C−X bonds and has resulted in a paradigm shift in synthetic strategy planning. The ruthenium catalysed C−C coupling reaction of propargyl alcohol and Michael acceptor has been demonstrated an enabling methodology for synthesis o α,β-unsaturated ketones as a single geometrical isomers of high yield in an atom-economical fashion. The synthesized α,β-unsaturated ketones are the precursor of poly-substituted piperidones and hexahydroisoquilininones which are the central backbone of many biologically active natural products and pharmaceutical drugs.en_US
dc.subjectRuthenium Catalyseden_US
dc.subjectAtom-Economic Transformationsen_US
dc.titleRuthenium-Catalysed Atom-Economic Transformationsen_US
dc.typeArticleen_US
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