Please use this identifier to cite or link to this item: http://hdl.handle.net/2080/2391
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dc.contributor.authorArakha, M-
dc.contributor.authorSaleem, M-
dc.contributor.authorMallick, B C-
dc.contributor.authorJha, S-
dc.date.accessioned2015-12-07T12:43:00Z-
dc.date.available2015-12-07T12:43:00Z-
dc.date.issued2015-04-
dc.identifier.citationThe International Conference on Small Science (ICSS 2015), Phuket, Thailand, 4-7 November 2015en_US
dc.identifier.urihttp://hdl.handle.net/2080/2391-
dc.descriptionCopyright belongs to proceeding publisheren_US
dc.description.abstractGram positive and Gram negative bacteria. ZnONPs with positive and negative surface potential are tested against different bacteria with varying surface potentials, ranging −14.7 to −23.6 mV. Chemically synthesized ZnONPs with positive surface potential show very high antimicrobial propensity with minimum inhibitory concentration of 50 and 100 μg/mL for Gram negative and positive bacterium, respectively. On other hand, ZnONPs of the same size but with negative surface potential show insignificant antimicrobial propensity against the studied bacteria. Unlike the positively charged nanoparticles, neither Zn2+ ion nor negatively charged ZnONP shows any significant inhibition in growth or morphology of the bacterium. Potential neutralization and colony forming unit studies together proved adverse effect of the resultant nano-bacterial interfacial potential on bacterial viability. Thus, ZnONP with positive surface potential upon interaction with negative surface potential of bacterial membrane enhances production of the reactive oxygen species and exerts mechanical stress on the membrane, resulting in the membrane depolarization. Our results show that the antimicrobial propensity of metal oxide nanoparticle mainly depends upon the interfacial potential, the potential resulting upon interaction of nanoparticle surface with bacterial membrane.en_US
dc.language.isoenen_US
dc.subjectAntimicrobial propensityen_US
dc.subjectNanoparticleen_US
dc.subjectZnOen_US
dc.titleThe effects of interfacial potential on antimicrobial propensity of ZnO nanoparticleen_US
dc.typeArticleen_US
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