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http://hdl.handle.net/2080/1076| Title: | Subtractive Genomic Approach to Identify Potential Drug Targets and Active Sites in Chlamydophila Pneumoniae |
| Authors: | Patnaik, S C Reddy, E H K Satpathy, G R |
| Keywords: | Chlamydophila pneumoniae, BLAST, MSA, homologous, homology modeling, active site |
| Issue Date: | 2009 |
| Citation: | National Workshop cum Training , Bioinformatics and Information Management in Aquaculture, 19-21 March, 2009. Central Institute of Freshwater Aquaculture, Indian Council of Agricultural Research Kausalyaganga, Bhubaneswar. page no:75-86. |
| Abstract: | Whole genome sequences of the human pathogen Chlamydophila pneumoniae and four other strains of same species were analyzed to identify common drug targets. A substractive genomic approach is applied to identify Holliday junction DNA helicase RuvB as the common non-human homologous gene among these four strains. A three-dimensional model of the Holliday junction DNA helicase RuvB protein was generated with homology modelling. The protein is analysed for identification of suitable target sites. |
| URI: | http://hdl.handle.net/2080/1076 |
| Appears in Collections: | Conference Papers |
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